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This line was subsequently modified by moving the line to a 4-hour acetaminophen concentration of 150 mcg/mL (current US cutoff) to increase the safety margin for treatment decisions

Subsequently, PI3K inhibition by the specific inhibitor wortmannin significantly reversed the anti-inflammatory and anti-apoptotic effects of APP/PS1mice

AMPK: mechanisms of cellular energy sensing and restoration of metabolic balance

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Cell 47 , 479493.e477 (2018)